Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.61 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610641 | 0.91 | TRPM8 (0.61) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14610915 | 0.90 | RAF1 (0.59) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14610733 | 0.89 | RAF1 (0.58) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL5305560 | 0.85 | MRGPRX4 (0.61) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14078347 | 0.84 | TRPM8 (0.69) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14610918 | 0.83 | TRPM8 (0.68) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14610711 | 0.83 | RAF1 (0.56) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14610939 | 0.83 | TRPM8 (0.52) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14078352 | 0.82 | TRPM8 (0.64) | RAF1MAP2K1NPC1RAB9AHPGD | |
| SCHEMBL14610712 | 0.81 | NPC1 (0.61) | RAF1MAP2K1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |