Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610640 | 0.88 | NR4A2 (0.47) | LPAR1LPAR5NR4A2MAOBPARP10 | |
| SCHEMBL14609997 | 0.86 | LPAR1 (0.48) | LPAR1LPAR5MAOBKMT2AALOX5 | |
| SCHEMBL14610653 | 0.85 | LPAR1 (0.52) | LPAR1LPAR5NR4A2PARP10NPC1 | |
| SCHEMBL14610644 | 0.85 | HPGD (0.51) | LPAR1LPAR5NPC1RAB9ALIMK2 | |
| SCHEMBL14610217 | 0.84 | TRPM8 (0.60) | LPAR1LPAR5NPC1RAB9ALIMK2 | |
| SCHEMBL14610600 | 0.84 | TRPM8 (0.48) | LPAR1LPAR5KMT2A | |
| SCHEMBL14611127 | 0.84 | LPAR1 (0.52) | LPAR1LPAR5SLC2A1LIMK2KMT2A | |
| SCHEMBL14610662 | 0.84 | LPAR1 (0.54) | LPAR1LPAR5NPC1RAB9ASLC2A1 | |
| SCHEMBL14610913 | 0.83 | LPAR1 (0.55) | LPAR1LPAR5NR4A2MAOBPARP10 | |
| SCHEMBL14610645 | 0.83 | LPAR1 (0.47) | LPAR1LPAR5SLC2A1LIMK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |