Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14610646 | 0.85 | LPAR1 (0.58) | LPAR1LPAR5ALOX5LIMK2PARP10 | |
| SCHEMBL14610219 | 0.84 | TRPM8 (0.56) | LPAR1NPC1 | |
| SCHEMBL14610727 | 0.82 | LPAR1 (0.65) | LPAR1LPAR5ALOX5PARP10NR4A1 | |
| SCHEMBL14610713 | 0.79 | LPAR1 (0.47) | LPAR1LPAR5ALOX5LIMK2 | |
| SCHEMBL14610711 | 0.76 | RAF1 (0.56) | LPAR1LPAR5NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14610913 | 0.76 | LPAR1 (0.55) | LPAR1LPAR5ALOX5PARP10NR4A2 | |
| SCHEMBL14610004 | 0.76 | TRPM8 (0.56) | LPAR1LPAR5NPC1 | |
| SCHEMBL14610746 | 0.76 | LPAR1 (0.47) | LPAR1LPAR5LIMK2SMN1; SMN2 | |
| SCHEMBL14609997 | 0.75 | LPAR1 (0.48) | LPAR1LPAR5ALOX5 | |
| SCHEMBL14610636 | 0.74 | EGFR (0.45) | LIMK2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017092-A1 | SUBSTITUTED 4-BENZYLOXY-BENZOIC ACID AMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-02-15 | — | — | WO | disclosed |