Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843709 | 0.85 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL5434268 | 0.85 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL13743046 | 0.84 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL683347 | 0.84 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL5150942 | 0.83 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL7387302 | 0.82 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL8565668 | 0.82 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8559031 | 0.82 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL14409680 | 0.82 | — | — | |
| SCHEMBL8563050 | 0.81 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019448-A2 | NITRIC OXIDE ENHANCING ANGIOTENSIN II ANTAGONIST COMPOUNDS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2007-02-15 | — | — | WO | disclosed |