Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611583 | 0.79 | ALDH1A1 (0.53) | MAPTPOLBLMNAHPGDL3MBTL1 | |
| SCHEMBL13067231 | 0.76 | MAPT (0.82) | MAPTPOLBLMNAHPGDL3MBTL1 | |
| SCHEMBL5654152 | 0.76 | MAPT (1.00) | MAPTPOLBLMNAHPGDL3MBTL1 | |
| SCHEMBL28269768 | 0.73 | MAPT (0.72) | MAPTPOLBLMNAHPGDL3MBTL1 | |
| SCHEMBL28269805 | 0.73 | MAPT (0.60) | MAPTPOLBLMNAHPGDL3MBTL1 | |
| SCHEMBL5657175 | 0.71 | MAPT (0.61) | MAPTPOLBLMNASMN1; SMN2CNR2 | |
| SCHEMBL31273836 | 0.71 | TDP1 (0.64) | MAPTPOLBLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL28532263 | 0.68 | MAPT (0.61) | MAPTPOLBLMNAHPGDL3MBTL1 | |
| SCHEMBL12271789 | 0.68 | MAPT (0.54) | MAPTPOLBLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6353566 | 0.68 | CTSB (0.51) | MAPTPOLBLMNAHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017114-A1 | NEW SUBSTITUTED AZATHYMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | MERLION PHARMACEUTICALS SA (CH) | 2007-02-15 | — | — | WO | disclosed |