Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 2/20 | 0.32 |
| ▸ | CMA1 | P23946 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611643 | 0.92 | ALDH1A1 (0.44) | POLBLMNAALDH1A1MAPTNPC1 | |
| SCHEMBL14611646 | 0.89 | KMT2A (0.34) | LMNAALDH1A1MAPTCNR2KMT2A | |
| SCHEMBL14611571 | 0.88 | STAT3 (0.35) | LMNAALDH1A1MAPTCNR2KMT2A | |
| SCHEMBL14611804 | 0.83 | KMT2A (0.38) | POLBLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL12957467 | 0.82 | POLB (0.46) | POLBLMNAALDH1A1MAPTNPC1 | |
| SCHEMBL14611569 | 0.81 | KMT2A (0.43) | POLBLMNAALDH1A1MAPTCNR1 | |
| SCHEMBL14611570 | 0.81 | KMT2A (0.34) | POLBLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL11956462 | 0.80 | STAT3 (0.35) | POLBLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL11957341 | 0.79 | CMA1 (0.39) | POLBLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL11948586 | 0.79 | ALDH1A1 (0.44) | POLBLMNAALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |