Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11956462 | 0.92 | STAT3 (0.35) | STAT3KMT2ATDP1HTTADRB2 | |
| SCHEMBL14611646 | 0.91 | KMT2A (0.34) | STAT3KMT2ATDP1HTTADRB2 | |
| SCHEMBL14611641 | 0.88 | POLB (0.38) | STAT3KMT2ATDP1HTTGNRHR | |
| SCHEMBL14611804 | 0.85 | KMT2A (0.38) | STAT3KMT2ATDP1HTTLMNA | |
| SCHEMBL14611569 | 0.83 | KMT2A (0.43) | KMT2ATDP1HTTGNRHRLMNA | |
| SCHEMBL14611570 | 0.82 | KMT2A (0.34) | STAT3KMT2ATDP1HTTLMNA | |
| SCHEMBL11957341 | 0.81 | CMA1 (0.39) | STAT3KMT2ATDP1HTTLMNA | |
| SCHEMBL14611643 | 0.80 | ALDH1A1 (0.44) | STAT3KMT2ATDP1HTTGNRHR | |
| SCHEMBL11948590 | 0.78 | STAT3 (0.36) | STAT3KMT2ATDP1HTTGNRHR | |
| SCHEMBL14611459 | 0.77 | KDM4E (0.38) | HTTLMNAALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |