Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TOP1 | P11387 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12957423 | 0.90 | METTL3 (0.42) | METTL3ALDH1A1DRD3HPGDLMNA | |
| SCHEMBL11948595 | 0.88 | METTL3 (0.54) | METTL3ALDH1A1DRD3HPGDLMNA | |
| SCHEMBL1045220 | 0.84 | METTL3 (0.46) | METTL3ALDH1A1DRD3HPGDLMNA | |
| SCHEMBL1045948 | 0.78 | METTL3 (0.54) | METTL3ALDH1A1DRD3HPGDLMNA | |
| SCHEMBL1043675 | 0.78 | MAPT (0.46) | METTL3ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL20343852 | 0.77 | METTL3 (0.57) | METTL3ALDH1A1HPGDPOLBKDM4E | |
| SCHEMBL1043831 | 0.77 | METTL3 (0.53) | METTL3ALDH1A1DRD3HPGDLMNA | |
| SCHEMBL1046027 | 0.77 | METTL3 (0.71) | METTL3ALDH1A1HPGDLMNAPOLB | |
| SCHEMBL14611459 | 0.76 | KDM4E (0.38) | METTL3ALDH1A1HPGDLMNAKDM4E | |
| SCHEMBL1044714 | 0.76 | METTL3 (0.50) | METTL3ALDH1A1DRD3HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |