Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045267 | 0.90 | METTL3 (0.44) | KDM4ECHRM1METTL3MAPTLMNA | |
| SCHEMBL1044601 | 0.81 | METTL3 (0.43) | KDM4ECHRM1METTL3ALDH1A1HPGD | |
| SCHEMBL3241137 | 0.79 | METTL3 (0.40) | METTL3MAPTHIF1A | |
| SCHEMBL11956951 | 0.78 | METTL3 (0.34) | METTL3 | |
| SCHEMBL13862191 | 0.77 | — | — | |
| SCHEMBL1045449 | 0.76 | METTL3 (0.43) | KDM4ECHRM1METTL3MAPTLMNA | |
| SCHEMBL1042873 | 0.76 | METTL3 (0.45) | KDM4ECHRM1METTL3HPGDMAPT | |
| SCHEMBL14611649 | 0.76 | METTL3 (0.42) | KDM4ECHRM1METTL3ALDH1A1HPGD | |
| SCHEMBL1046140 | 0.76 | METTL3 (0.44) | KDM4ECHRM1METTL3MAPTLMNA | |
| SCHEMBL1046378 | 0.75 | METTL3 (0.54) | KDM4ECHRM1METTL3MAPTTOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176220-B2 | 4-oxoquinoline compound and use thereof as pharmaceutical agent | JAPAN TOBACCO INC. (JP) | 2007-02-13 | — | — | US | disclosed |