Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290573 | 0.77 | NPSR1 (0.43) | MAPTKMT2AMEN1POLBLMNA | |
| SCHEMBL5299057 | 0.76 | HSP90AA1 (0.38) | KMT2AMEN1HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14611722 | 0.76 | POLB (0.34) | KMT2AMEN1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL16743571 | 0.76 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11635996 | 0.75 | NPSR1 (0.47) | MAPTKMT2AMEN1POLBLMNA | |
| SCHEMBL4683449 | 0.74 | KMT2A (0.43) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL17156225 | 0.73 | MAPT (0.35) | MAPTKMT2AMEN1POLBHTT | |
| Hydrochloric Acid SCHEMBL11318178 | 0.73 | KMT2A (0.42) | KMT2AMEN1ALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL14611721 | 0.73 | ALDH1A1 (0.42) | MAPTKMT2AMEN1LMNAHTT | |
| SCHEMBL11418377 | 0.72 | HSP90AB1 (0.41) | MAPTKMT2AMEN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017114-A1 | NEW SUBSTITUTED AZATHYMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | MERLION PHARMACEUTICALS SA (CH) | 2007-02-15 | — | — | WO | disclosed |