Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611721 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDHTTRAB9ASMN1; SMN2 | |
| SCHEMBL14611718 | 0.81 | USP2 (0.43) | ALDH1A1HPGDTSHRHTTRAB9A | |
| SCHEMBL14611586 | 0.79 | LMNA (0.41) | ALDH1A1HPGDRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL3236065 | 0.77 | MAPT (0.45) | ALDH1A1HPGDTSHRMAPK1RAB9A | |
| SCHEMBL14611587 | 0.77 | KDM1A (0.34) | ALDH1A1HPGDRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL14611585 | 0.76 | POLB (0.33) | ALDH1A1RAB9AHSD17B10TDP1KDM4E | |
| SCHEMBL14611713 | 0.76 | MAPT (0.37) | ALDH1A1HPGDMAPK1HTTSMN1; SMN2 | |
| SCHEMBL14611583 | 0.73 | ALDH1A1 (0.53) | HSP90AA1ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL7020481 | 0.72 | KMT2A (0.41) | HSP90AA1ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL5305067 | 0.72 | PDPK1 (0.35) | HSP90AA1ALDH1A1ABCB1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017114-A1 | NEW SUBSTITUTED AZATHYMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | MERLION PHARMACEUTICALS SA (CH) | 2007-02-15 | — | — | WO | claimed |
| WO-2007017114-A1 | NEW SUBSTITUTED AZATHYMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | MERLION PHARMACEUTICALS SA (CH) | 2007-02-15 | — | — | WO | disclosed |
| WO-2007017114-A1 | NEW SUBSTITUTED AZATHYMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIOUS DISEASES | MERLION PHARMACEUTICALS SA (CH) | 2007-02-15 | — | — | WO | disclosed |