SCHEMBL14613152

SCHEMBL14613152

CNc1nc(CI)nc(CI)n1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15739276 0.80 CYP1A2 (0.43) PDE4ACYP1A2CYP2C19
SCHEMBL14097042 0.76 PDE4A (0.36) PDE4ACYP1A2CYP2C19TDP1
SCHEMBL17050016 0.74 PDE4A (0.35) PDE4ACYP1A2CYP2C19TDP1
SCHEMBL18903179 0.70 LMNA (0.54) CYP1A2CYP2C19
SCHEMBL33146 0.69 PDE4A (0.48) PDE4ACYP1A2CYP2C19TDP1
SCHEMBL27871771 0.66 PDE4A (0.46) PDE4ACYP1A2CYP2C19TDP1
SCHEMBL14434419 0.63 CASP1 (0.46) CYP1A2
SCHEMBL7399881 0.62 PDE4A (0.52) PDE4ACYP1A2CYP2C19TDP1
SCHEMBL16574342 0.61 CA1 (0.41) PDE4ACYP1A2CYP2C19TDP1
SCHEMBL14869406 0.59 LMNA (0.61) PDE4ACYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1757933-A1 METHOD FOR THE DETERMINATION OF BODY ODOR Kao Corporation (JP) 2007-02-28 EP disclosed