Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22185251 | 0.87 | PLA2G4A (0.48) | CYP1A2CYP2A6ALOX15BCYP3A4GAA | |
| SCHEMBL12160840 | 0.79 | BIRC5 (0.61) | CYP1A2CYP2A6ALOX15BCYP3A4GAA | |
| SCHEMBL21257470 | 0.79 | BIRC5 (0.47) | CYP1A2CYP2A6BIRC5F2F10 | |
| SCHEMBL5661673 | 0.77 | FGFR1 (0.47) | CYP1A2CYP2A6GAAL3MBTL1BIRC5 | |
| SCHEMBL23982987 | 0.77 | HPGD (0.55) | GAAL3MBTL1PLA2G4ANOTUMHDAC8 | |
| SCHEMBL18926984 | 0.76 | KMT2A (0.47) | GAACYP2D6CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL10289623 | 0.75 | HTR6 (0.57) | CYP1A2CYP2A6HTR7HDAC8HDAC3 | |
| SCHEMBL15712770 | 0.74 | SMN1; SMN2 (0.55) | CYP3A4L3MBTL1BIRC5PLA2G4AHDAC8 | |
| SCHEMBL15741202 | 0.74 | CDC7 (0.49) | CYP1A2CYP2A6ALOX15BCYP3A4CYP2D6 | |
| SCHEMBL157573 | 0.74 | BIRC5 (0.62) | CYP2A6GAABIRC5PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176201-B2 | Modulation of anxiety through blockade of anandamide hydrolysis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-13 | — | — | US | disclosed |