Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 19/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583978 | 0.81 | F2R (0.77) | F2RF2 | |
| SCHEMBL14583987 | 0.75 | F2R (0.55) | F2RF2 | |
| SCHEMBL4263176 | 0.72 | F2R (0.85) | F2RF2 | |
| SCHEMBL14614228 | 0.71 | F2R (0.47) | F2RF2 | |
| SCHEMBL14583974 | 0.71 | F2R (0.53) | F2RF2 | |
| Rwj-58259 SCHEMBL14090275 | 0.71 | F2R (0.83) | F2RF2 | |
| SCHEMBL14583980 | 0.67 | F2R (0.57) | F2RF2 | |
| SCHEMBL14090284 | 0.66 | F2R (0.76) | F2RF2 | |
| SCHEMBL12340158 | 0.65 | F2R (0.65) | F2RF2 | |
| SCHEMBL14090282 | 0.64 | F2R (0.74) | F2RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |