Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 14/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583992 | 0.81 | F2R (0.67) | F2RF2 | |
| SCHEMBL14090294 | 0.73 | F2R (0.68) | F2RF2 | |
| SCHEMBL14614029 | 0.71 | F2R (0.52) | F2RF2 | |
| SCHEMBL14583983 | 0.68 | F2R (0.82) | F2RF2 | |
| SCHEMBL14090286 | 0.68 | F2R (0.68) | F2RF2 | |
| SCHEMBL14114981 | 0.68 | GRIA1 (0.46) | KLKB1GRIA1PLG | |
| Rwj-58259 SCHEMBL14090275 | 0.62 | F2R (0.83) | F2RF2 | |
| SCHEMBL4263176 | 0.61 | F2R (0.85) | F2RF2 | |
| SCHEMBL14090288 | 0.61 | GRIA1 (0.41) | GRIA1PLG | |
| SCHEMBL20873706 | 0.61 | KLKB1 (0.77) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |