Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483071 | 0.72 | NR1I2 (0.37) | RXRAGRIN1GRIN2B | |
| SCHEMBL5116625 | 0.69 | NOTUM (0.47) | RXRAGRIN1GRIN2B | |
| SCHEMBL31014601 | 0.59 | LMNA (0.43) | — | |
| SCHEMBL20303483 | 0.55 | PSEN1 (0.44) | — | |
| SCHEMBL13877400 | 0.55 | APLNR (0.46) | — | |
| SCHEMBL13876351 | 0.55 | APLNR (0.55) | — | |
| SCHEMBL20303473 | 0.55 | PSEN1 (0.38) | — | |
| SCHEMBL32682776 | 0.55 | PSEN1 (0.38) | — | |
| SCHEMBL18263511 | 0.55 | APLNR (0.46) | — | |
| SCHEMBL13876349 | 0.55 | APLNR (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021573-A1 | SUBSTITUTED PIPERAZINES AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2007-02-22 | — | — | WO | disclosed |