Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14614714 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNA4MEN1ALOX15KMT2A | |
| SCHEMBL18795872 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNA4MEN1ALOX15KMT2A | |
| SCHEMBL29364445 | 1.00 | CHRNB2 (0.38) | CHRNB2CHRNA4MEN1ALOX15KMT2A | |
| SCHEMBL20538855 | 0.84 | CHRNB2 (0.39) | CHRNB2CHRNA4MEN1ALOX15KMT2A | |
| SCHEMBL31247610 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNA4MEN1ALOX15KMT2A | |
| SCHEMBL868299 | 0.79 | GRM5 (0.52) | CHRNB2CHRNA4CYP1A2TSHRGRM5 | |
| SCHEMBL12891722 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA4MEN1KMT2AGRM5 | |
| SCHEMBL12891724 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA4MEN1KMT2AGRM5 | |
| SCHEMBL19053737 | 0.79 | GRM5 (0.36) | MEN1ALOX15KMT2ACYP1A2TSHR | |
| SCHEMBL20539382 | 0.76 | SIRT1 (0.40) | CHRNB2CHRNA4P2RX7KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757591-A1 | CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |