SCHEMBL14614742

SCHEMBL14614742

CCC(CN)N1CCC(N)CC1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.36
GNAO1 P09471 2/20 0.36
GNAI1 P63096 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1742773 0.89 GNAI3 (0.39) GNAI3GNAO1GNAI1
SCHEMBL5554372 0.80 GNAI3 (0.34) GNAI3GNAO1GNAI1
SCHEMBL4035791 0.78 SLC6A4 (0.36)
SCHEMBL13638195 0.77 GNAI3 (0.41) GNAI3GNAO1GNAI1
SCHEMBL1892265 0.76 SLC6A4 (0.35)
SCHEMBL103035 0.74 IDO1 (0.37)
SCHEMBL18557446 0.74 HRH3 (0.41) GNAI3GNAO1GNAI1
SCHEMBL7177989 0.72 DPP4 (0.39)
SCHEMBL28946119 0.72 GNAI3 (0.37) GNAI3GNAO1GNAI1
SCHEMBL4090482 0.72 GNAI3 (0.37) GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7173054-B2 Respiratory syncytial virus replication inhibitors JANSSEN PHARMACEUTICA, N.V. (BE) 2007-02-06 US disclosed