Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23252498 | 0.89 | GNAI3 (0.36) | GNAI3GNAO1GNAI1DPP4 | |
| SCHEMBL11403240 | 0.86 | GNAI3 (0.50) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL19779350 | 0.84 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL20621280 | 0.84 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL23490184 | 0.84 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL19779490 | 0.84 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL1742773 | 0.82 | GNAI3 (0.39) | GNAI3GNAO1GNAI1SPHK1HRH3 | |
| SCHEMBL8262509 | 0.80 | PHGDH (0.34) | HRH3 | |
| SCHEMBL21776125 | 0.80 | GNAI3 (0.45) | GNAI3GNAO1GNAI1SPHK1DPP4 | |
| SCHEMBL7243183 | 0.79 | GNAI3 (0.39) | GNAI3GNAO1GNAI1SPHK1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3753932-A1 | SUBSTITUTED BICYCLIC DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-12-23 | — | — | EP | disclosed |
| US-7612064-B2 | Sulfopyrroles | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-03 | — | — | US | disclosed |