Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 4/20 | 0.46 |
| ▸ | CCR5 | P51681 | 4/20 | 0.46 |
| ▸ | CCR8 | P51685 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197885 | 0.88 | HSP90AA1 (0.66) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| SCHEMBL4735238 | 0.82 | HSP90AA1 (0.59) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| SCHEMBL1366769 | 0.81 | HSP90AA1 (0.58) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| SCHEMBL6130670 | 0.79 | HSP90AA1 (0.56) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| SCHEMBL2711382 | 0.78 | CCR1 (0.77) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| Dipyridyl SCHEMBL9014122 | 0.78 | CCR1 (0.77) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| Dipyridyl SCHEMBL9014402 | 0.78 | CCR1 (0.77) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| Caerulomycinonitrile SCHEMBL8515198 | 0.77 | HSP90AA1 (0.54) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| SCHEMBL8513636 | 0.77 | HSP90AA1 (0.54) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 | |
| Caerulomycin F SCHEMBL29884857 | 0.77 | HSP90AA1 (0.58) | HSP90AA1NPC1RAB9ARUNX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749552-A1 | Use of collismycin and derivatives thereof as oxidative stress inhibitors | Neuropharma S.A. (ES) | 2007-02-07 | — | — | EP | disclosed |