Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.77 |
| ▸ | CCR5 | P51681 | 4/20 | 0.77 |
| ▸ | CCR8 | P51685 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | NOS2 | P35228 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL9014122 | 1.00 | CCR1 (0.77) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL2711382 | 1.00 | CCR1 (0.77) | CCR1CCR5CCR8KDM4ELMNA | |
| SCHEMBL29395249 | 0.88 | CCR1 (1.00) | CCR1CCR5CCR8CYP1A2NPC1 | |
| SCHEMBL182529 | 0.88 | CCR1 (1.00) | CCR1CCR5CCR8CYP1A2NPC1 | |
| Methane SCHEMBL21386924 | 0.86 | CCR1 (0.95) | CCR1CCR5CCR8CYP1A2NPC1 | |
| Hydrochloric Acid SCHEMBL29903189 | 0.86 | CCR1 (0.95) | CCR1CCR5CCR8CYP1A2NPC1 | |
| SCHEMBL8746042 | 0.86 | CCR1 (0.95) | CCR1CCR5CCR8CYP1A2NPC1 | |
| SCHEMBL9135460 | 0.86 | CCR1 (0.95) | CCR1CCR5CCR8CYP1A2NPC1 | |
| SCHEMBL28212407 | 0.86 | CCR1 (0.95) | CCR1CCR5CCR8CYP1A2NPC1 | |
| SCHEMBL197885 | 0.85 | HSP90AA1 (0.66) | CCR1CCR5CCR8KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526603-B1 | Use of Mono, Bis or Tris (2,2'-substituted Bipyridine) complexes of a transition metal as mediators for current sensors | ASULAB SA (CH) | 1996-12-04 | — | — | EP | claimed |