Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.66 |
| ▸ | CCR1 | P32246 | 4/20 | 0.58 |
| ▸ | CCR5 | P51681 | 4/20 | 0.58 |
| ▸ | CCR8 | P51685 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.57 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735238 | 0.90 | HSP90AA1 (0.59) | HSP90AA1CCR1CCR5CCR8LMNA | |
| SCHEMBL6130670 | 0.90 | HSP90AA1 (0.56) | HSP90AA1CCR1CCR5CCR8LMNA | |
| SCHEMBL1366769 | 0.88 | HSP90AA1 (0.58) | HSP90AA1CCR1CCR5CCR8LMNA | |
| SCHEMBL14615313 | 0.88 | HSP90AA1 (0.58) | HSP90AA1CCR1CCR5CCR8LMNA | |
| SCHEMBL9341045 | 0.87 | HSP90AA1 (0.69) | HSP90AA1CCR1CCR5CCR8LMNA | |
| SCHEMBL2711382 | 0.85 | CCR1 (0.77) | HSP90AA1CCR1CCR5CCR8LMNA | |
| Dipyridyl SCHEMBL9014122 | 0.85 | CCR1 (0.77) | HSP90AA1CCR1CCR5CCR8LMNA | |
| Dipyridyl SCHEMBL9014402 | 0.85 | CCR1 (0.77) | HSP90AA1CCR1CCR5CCR8LMNA | |
| SCHEMBL7454751 | 0.84 | NPC1 (0.57) | HSP90AA1CCR1CCR5CCR8LMNA | |
| SCHEMBL31260432 | 0.84 | NPC1 (0.57) | HSP90AA1CCR1CCR5CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9891185-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2018-02-13 | — | — | US | disclosed |
| US-9662057-B2 | Integrated sample acquisition and analyte measurement method | ABBOTT DIABETES CARE INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-20160334356-A1 | Small Volume In Vitro Analyte Sensor | THERASENSE, INC. | 2016-11-17 | — | — | US | disclosed |
| US-20160235350-A1 | Integrated Sample Acquisition and Analyte Measurement Device | THERASENSE, INC. | 2016-08-18 | — | — | US | disclosed |
| US-9341591-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9316609-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-04-19 | — | — | US | disclosed |
| US-9291592-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-9271669-B2 | Method for integrated sample acquisition and analyte measurement device | ABBOTT DIABETES CARE INC. (US) | 2016-03-01 | — | — | US | disclosed |
| US-9234863-B2 | Small volume in vitro analyte sensor | ABBOTT DIABETES CARE INC. (US) | 2016-01-12 | — | — | US | disclosed |
| US-9188590-B2 | Labeled transition metal complexes | LEICA BIOSYSTEMS NEWCASTLE LTD. (GB) | 2015-11-17 | — | — | US | disclosed |
| US-20030199744-A1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. (US) | 2003-10-23 | — | — | US | disclosed |
| US-6618934-B1 | Method of manufacturing small volume in vitro analyte sensor | THERASENSE, INC. | 2003-09-16 | — | — | US | disclosed |
| US-6592745-B1 | Analytical sensors for the detection of bioanalytes in a small volume sample; to monitor glucose in diabetic patients and lactate during critical care | THERASENSE, INC. | 2003-07-15 | — | — | US | disclosed |
| US-6591125-B1 | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator | THERASENSE, INC. | 2003-07-08 | — | — | US | disclosed |
| US-6461496-B1 | BLOOD GLUCOSE | THERASENSE, INC. | 2002-10-08 | — | — | US | disclosed |
| EP-0885233-B1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION (GB) | 2002-06-19 | — | — | EP | disclosed |
| US-20020013306-A1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION LIMITED (GB) | 2002-01-31 | — | — | US | disclosed |
| US-6338790-B1 | DETECTION OF BIOANALYTES IN A SMALL VOLUME SAMPLE; CONCENTRATION OF A BIOMOLECULE, SUCH AS GLUCOSE OR LACTATE, USING TECHNIQUES SUCH AS COULOMETRY, AMPEROMETRY, AND POTENTIOMETRY. AN ENZYME CAPABLE OF CATALYZING THE | THERASENSE, INC. | 2002-01-15 | — | — | US | disclosed |
| EP-1164138-A1 | Terpyridine-platinum (II) complexes | ISIS INNOVATION LIMITED (GB) | 2001-12-19 | — | — | EP | disclosed |
| US-6299757-B1 | ANALYTICAL SENSORS FOR THE DETECTION OF BIOANALYTES; ESPECIALLY MONITORING GLUCOSE LEVELS IN DIABETIC PATIENTS | THERASENSE, INC. | 2001-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013306-A1 | TERPYRIDINE-PLATINUM(II) COMPLEXES | TOP2A, TOP1, TOP2B | HSP90AA1 1133/4885CCR1 1921/4885CCR5 884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.