Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.51 |
| ▸ | MC1R | Q01726 | 5/20 | 0.38 |
| ▸ | MC5R | P33032 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.37 |
| ▸ | KLK1 | P06870 | 2/20 | 0.37 |
| ▸ | MC4R | P32245 | 3/20 | 0.36 |
| ▸ | MC3R | P41968 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | FCER2 | P06734 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HPN | P05981 | 1/20 | 0.34 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL738034 | 0.93 | GHSR (0.60) | GHSRMC1RMC5RKLKB1KLK1 | |
| SCHEMBL737835 | 0.91 | GHSR (0.60) | GHSRMC1RMC5RKLKB1KLK1 | |
| SCHEMBL737925 | 0.90 | GHSR (0.60) | GHSRMC1RMC5RKLKB1KLK1 | |
| SCHEMBL736832 | 0.88 | GHSR (0.60) | GHSRMC1RMC5RKLKB1KLK1 | |
| SCHEMBL739069 | 0.83 | GHSR (0.71) | GHSRKLKB1KLK1MMP9MMP8 | |
| SCHEMBL738022 | 0.82 | GHSR (0.64) | GHSRKLKB1KLK1MMP9MMP8 | |
| SCHEMBL737042 | 0.82 | GHSR (0.64) | GHSRKLKB1KLK1MMP9MMP8 | |
| SCHEMBL14615567 | 0.81 | GHSR (0.52) | GHSRMC1RMC5RKLKB1KLK1 | |
| SCHEMBL739675 | 0.81 | GHSR (0.71) | GHSRKLKB1KLK1MMP9MMP8 | |
| SCHEMBL739067 | 0.80 | GHSR (0.64) | GHSRKLKB1KLK1MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014258-A2 | GROWTH HORMONE SECRETAGOGUES | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2007-02-01 | — | — | WO | disclosed |