Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.64 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737042 | 1.00 | GHSR (0.64) | GHSRTACR1MMP9KLKB1MMP8 | |
| SCHEMBL739069 | 0.94 | GHSR (0.71) | GHSRTACR1MMP9KLKB1MMP8 | |
| SCHEMBL737831 | 0.90 | GHSR (0.64) | GHSRMMP9KLKB1MMP8MMP2 | |
| SCHEMBL739067 | 0.90 | GHSR (0.64) | GHSRMMP9KLKB1MMP8MMP2 | |
| SCHEMBL737925 | 0.89 | GHSR (0.60) | GHSRTACR1MMP9KLKB1MMP8 | |
| SCHEMBL738034 | 0.89 | GHSR (0.60) | GHSRTACR1MMP9KLKB1MMP8 | |
| SCHEMBL738032 | 0.88 | GHSR (0.85) | GHSRTACR1MMP9MMP8 | |
| SCHEMBL739684 | 0.88 | GHSR (0.85) | GHSRTACR1MMP9MMP8 | |
| SCHEMBL739284 | 0.84 | GHSR (0.63) | GHSRTACR1MMP9KLKB1MMP8 | |
| SCHEMBL738004 | 0.84 | GHSR (0.63) | GHSRTACR1MMP9KLKB1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138218-B2 | Growth hormone secretagogues | IPSEN PHARMA S.A.S. (FR) | 2012-03-20 | — | — | US | disclosed |
| US-20090131478-A1 | Growth Hormone Secretagogues | IPSEN PHARMA S.A.S. (FR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131478-A1 | Growth Hormone Secretagogues | GHSR, GHRHR, GHITM | GHSR 1/4885TACR1 489/4885MMP9 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.