Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.48 |
| ▸ | ITGAV | P06756 | 11/20 | 0.48 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 2/20 | 0.46 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.46 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | MC1R | Q01726 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14585801 | 0.91 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL7744062 | 0.91 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL7743645 | 0.91 | ITGB3 (0.54) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL7746264 | 0.87 | ITGB3 (0.47) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL8363710 | 0.87 | ITGB3 (0.45) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL25474158 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL19605449 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL29973120 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| Cyclorgdfv SCHEMBL19605549 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL7738196 | 0.86 | PLAU (0.50) | ITGB3ITGAVITGB5ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179446-B2 | Simultaneous imaging of cardiac perfusion and a vitronectin receptor targeted imaging agent | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-02-20 | — | — | US | disclosed |