Cyclorgdfv

Cyclorgdfv

SCHEMBL29973120

CC(C)[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC1=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ ITGB3 P05106 10/20 0.58
▸ ITGAV P06756 10/20 0.58
▸ ITGB5 P18084 6/20 0.58
▸ ITGB1 P05556 2/20 0.58
▸ ITGA5 P08648 2/20 0.58
▸ ITGA2B P08514 2/20 0.56
▸ ITGB6 P18564 2/20 0.56
▸ KDM4A O75164 1/20 0.55
▸ CTSG P08311 2/20 0.55
▸ KRAS P01116 1/20 0.54
▸ MC4R P32245 6/20 0.53
▸ MC5R P33032 6/20 0.53
▸ MC3R P41968 6/20 0.53
▸ MC1R Q01726 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclorgdfv SCHEMBL19605449 1.00 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5
Cyclorgdfv SCHEMBL19605549 1.00 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5
Cyclorgdfv SCHEMBL25474158 1.00 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL25473422 0.94 KDM4A (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL20888358 0.93 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL21766911 0.93 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL19605458 0.93 ITGB3 (0.58) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL22970200 0.90 ITGB3 (0.56) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL20888349 0.90 ITGB3 (0.52) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL19605463 0.90 MC4R (0.57) ITGB3ITGAVITGB5ITGB1ITGA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036218-B2 Modulators of airway basal cells for the treatment or prevention of lung diseases Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2024-07-16 — — US claimed
EP-4731273-A2 HYDROGEL FORMULATIONS AND METHODS OF USE THEREOF Tempo Therapeutics, Inc. (US) 2026-04-29 — — EP disclosed
US-20260007802-A1 ANNEALED MICROGEL PARTICLE SYSTEMS AND METHODS TEMPO THERAPEUTICS INC (US) 2026-01-08 — — US disclosed
EP-4654940-A1 ANNEALED MICROGEL PARTICLE SYSTEMS AND METHODS Tempo Therapeutics, Inc. (US) 2025-12-03 — — EP disclosed
WO-2025006482-A2 HYDROGEL FORMULATIONS AND METHODS OF USE THEREOF TEMPO THERAPEUTICS, INC. (US) 2025-01-02 — — WO disclosed
WO-2024159142-A1 ANNEALED MICROGEL PARTICLE SYSTEMS AND METHODS TEMPO THERAPEUTICS, INC. (US) 2024-08-02 — — WO disclosed
EP-4067370-A1 HIGH PENETRATION PRODRUG COMPOSITIONS OF PEPTIDES AND PEPTIDE RELATED COMPOUNDS Yu, Chongxi (US) 2022-10-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007802-A1 ANNEALED MICROGEL PARTICLE SYSTEMS AND METHODS VCL, CD44, FGB ITGB3 460/4885ITGAV 664/4885ITGB5 820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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