⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3863769 | 0.81 | — | — | |
| SCHEMBL550638 | 0.81 | — | — | |
| SCHEMBL550594 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL629821 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL629822 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL15422026 | 0.79 | — | — | |
| SCHEMBL6904890 | 0.74 | TSHR (0.50) | — | |
| SCHEMBL15702330 | 0.74 | TSHR (0.50) | — | |
| SCHEMBL15888358 | 0.74 | — | — | |
| SCHEMBL18029831 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362244-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
| US-9238039-B2 | Pyrazolo[1,5-A]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2016-01-19 | — | — | US | disclosed |
| US-20140072554-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2014-03-13 | — | — | US | disclosed |
| US-8486938-B2 | Pyrazolo[1,5-a]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| WO-2007014848-A2 | STABILIZATION OF BODY-CARE AND HOUSEHOLD PRODUCTS AGAINST DEGRADATION BY UV RADIATION USING MEROCYANINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-02-08 | — | — | WO | disclosed |