Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017995 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRGAAMAPTTDP1 | |
| SCHEMBL3939343 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TSHRGAAMAPTTDP1 | |
| SCHEMBL11020359 | 0.80 | GAA (0.53) | ALDH1A1TSHRGAAMAPTTDP1 | |
| SCHEMBL7379537 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRGAAMAPTTDP1 | |
| SCHEMBL4408344 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRGAAMAPTTDP1 | |
| SCHEMBL28242825 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRGAAMAPTTDP1 | |
| SCHEMBL8121589 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRGAAMAPTTDP1 | |
| SCHEMBL13300766 | 0.77 | CTSK (0.52) | MEN1KMT2ALMNACTSK | |
| SCHEMBL7986231 | 0.77 | CTSK (0.52) | MEN1KMT2ALMNACTSK | |
| SCHEMBL30305384 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRGAAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183281-B2 | Sulfonylquinoxalone derivatives and related compounds as bradykinin antagonists | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-27 | — | — | US | disclosed |