SCHEMBL14615870

SCHEMBL14615870

C[C@H]1C[C@@H](COC(=O)c2ccccc2)O[C@H]1n1cnc2c(Cl)ncnc21

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TYMP P19971 1/20 0.50
▸ LMNA P02545 1/20 0.49
▸ STING1 Q86WV6 2/20 0.42
▸ ABCB1 P08183 1/20 0.42
▸ GSK3A P49840 1/20 0.41
▸ RPS6KA3 P51812 1/20 0.41
▸ MAPK14 Q16539 1/20 0.41
▸ P2RX3 P56373 1/20 0.41
▸ P2RX4 Q99571 1/20 0.41
▸ P2RX2 Q9UBL9 1/20 0.41
▸ NPC1 O15118 1/20 0.41
▸ POLB P06746 1/20 0.40
▸ AHCY P23526 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20059072 1.00 TYMP (0.50) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL3163915 0.89 LMNA (0.53) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL13970745 0.89 LMNA (0.53) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL3163908 0.89 LMNA (0.53) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL14593730 0.88 LMNA (0.46) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL5389035 0.88 LMNA (0.46) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL5389026 0.88 LMNA (0.46) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL20610917 0.87 NT5E (0.44) LMNANPC1POLB
SCHEMBL24673394 0.85 LMNA (0.46) TYMPLMNASTING1ABCB1GSK3A
SCHEMBL22798386 0.85 LMNA (0.46) TYMPLMNASTING1ABCB1GSK3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070032448-A1 Sugar modified nucleosides as viral replication inhibitors RIBAPHARM INC. 2007-02-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032448-A1 Sugar modified nucleosides as viral replication inhibitors PNP, MTAP, GALE TYMP 16/4885LMNA 4188/4885STING1 472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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