Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AHCY | P23526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14615870 | 1.00 | TYMP (0.50) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL3163915 | 0.89 | LMNA (0.53) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL13970745 | 0.89 | LMNA (0.53) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL3163908 | 0.89 | LMNA (0.53) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL14593730 | 0.88 | LMNA (0.46) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL5389035 | 0.88 | LMNA (0.46) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL5389026 | 0.88 | LMNA (0.46) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL20610917 | 0.87 | NT5E (0.44) | LMNANPC1POLB | |
| SCHEMBL24673394 | 0.85 | LMNA (0.46) | TYMPLMNASTING1ABCB1GSK3A | |
| SCHEMBL22798386 | 0.85 | LMNA (0.46) | TYMPLMNASTING1ABCB1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |