Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3448866 | 1.00 | ALDH1A1 (0.63) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL2235887 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL13585322 | 0.89 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL3449699 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAGBA1TSHRSLC1A3 | |
| SCHEMBL3730989 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAGBA1TSHRSLC1A3 | |
| SCHEMBL9497964 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAGBA1TSHRSLC1A3 | |
| Hydrochloric Acid SCHEMBL4438846 | 0.86 | ALDH1A1 (0.54) | ALDH1A1LMNAGBA1TSHRSLC1A3 | |
| SCHEMBL13657512 | 0.85 | FOLH1 (0.46) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL26641058 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL29557249 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020636-A1 | PRINTABLE MATERIALS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2007-02-22 | — | — | WO | disclosed |
| CN-1109780-A | Sustained-release preparation of anti-endothelin substance | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-10-11 | — | — | CN | disclosed |