SCHEMBL29557249

SCHEMBL29557249

N[C@@H](CCCCNS(=O)(=O)c1ccc([N+](=O)[O-])cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
MAPT P10636 4/20 0.54
SLC1A3 P43003 1/20 0.53
SLC1A2 P43004 1/20 0.53
SLC1A1 P43005 1/20 0.53
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
GAA P10253 2/20 0.50
PKM P14618 2/20 0.50
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRM4 Q14833 1/20 0.46
RAB9A P51151 1/20 0.46
TBXAS1 P24557 2/20 0.46
MMP1 P03956 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26641058 1.00 ALDH1A1 (0.54) ALDH1A1MAPTSLC1A3SLC1A2SLC1A1
SCHEMBL26641062 1.00 ALDH1A1 (0.54) ALDH1A1MAPTSLC1A3SLC1A2SLC1A1
SCHEMBL29814950 0.96 ALDH1A1 (0.55) ALDH1A1MAPTSLC1A3SLC1A2SLC1A1
SCHEMBL29814995 0.96 ALDH1A1 (0.55) ALDH1A1MAPTSLC1A3SLC1A2SLC1A1
SCHEMBL29814701 0.91 SLC1A3 (0.56) ALDH1A1MAPTSLC1A3SLC1A2SLC1A1
SCHEMBL29814907 0.91 SLC1A3 (0.56) ALDH1A1MAPTSLC1A3SLC1A2SLC1A1
SCHEMBL14615873 0.84 ALDH1A1 (0.63) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL3448866 0.84 ALDH1A1 (0.63) ALDH1A1SLC1A3SLC1A2SLC1A1KMT2A
SCHEMBL3449699 0.83 ALDH1A1 (0.55) ALDH1A1SLC1A3SLC1A2SLC1A1CA2
SCHEMBL9497964 0.83 ALDH1A1 (0.55) ALDH1A1SLC1A3SLC1A2SLC1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4440592-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2024-10-09 EP claimed
WO-2023099669-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2023-06-08 WO claimed
WO-2025091122-A1 CYCLIC PEPTIDE ANALOGS OF MELANOCORTIN AND USES THEREOF THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2025-05-08 WO disclosed
EP-4504732-A2 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF University of Connecticut (US) 2025-02-12 EP disclosed
EP-4499663-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS Provincial Health Services Authority (CA) 2025-02-05 EP disclosed
EP-4440592-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2024-10-09 EP disclosed
EP-4422695-A1 METHODS FOR PRODUCING ANTIBODY-LINKER CONJUGATES Araris Biotech AG (CH) 2024-09-04 EP disclosed
WO-2023192975-A2 NANOMATERIAL DELIVERY VEHICLE AND METHOD OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2023-10-05 WO disclosed
WO-2023178449-A1 RADIOLABELED COMPOUNDS FOR IN VIVO IMAGING OF GASTRIN-RELEASING PEPTIDE RECEPTOR (GRPR) AND TREATMENT OF GRPR-RELATED DISORDERS PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2023-09-28 WO disclosed
EP-4232095-A1 MEANS AND METHODS FOR PRODUCING ANTIBODY-LINKER CONJUGATES Araris Biotech AG (CH) 2023-08-30 EP disclosed
EP-4228707-A1 NANOMATERIAL AND METHODS OF USE THEREOF University of Connecticut (US) 2023-08-23 EP disclosed
WO-2023099669-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2023-06-08 WO disclosed
WO-2023072934-A1 METHODS FOR PRODUCING ANTIBODY-LINKER CONJUGATES ARARIS BIOTECH AG (CH) 2023-05-04 WO disclosed
US-11395857-B2 Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy PROVINCIAL HEALTH SERVICES AUTHORITY (CA) 2022-07-26 US disclosed
WO-2022084560-A1 MEANS AND METHODS FOR PRODUCING ANTIBODY-LINKER CONJUGATES ARARIS BIOTECH AG (CH) 2022-04-28 WO disclosed
WO-2022081721-A1 NANOMATERIAL AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2022-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11395857-B2 Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte-stimulating hormone analogues for imaging or therapy MC1R, MC5R, MC3R ALDH1A1 3276/4885MAPT 3960/4885SLC1A3 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.