Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92647 | 1.00 | EPHX1 (0.52) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL19198224 | 0.93 | EPHX1 (0.56) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL27334711 | 0.93 | EPHX1 (0.56) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL18758414 | 0.93 | EPHX1 (0.56) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL19427053 | 0.91 | EPHX1 (0.61) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL17808443 | 0.90 | EPHX1 (0.46) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL7026506 | 0.90 | EPHX1 (0.46) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL21985348 | 0.88 | EPHX1 (0.64) | EPHX1ACE2LMNAALDH1A1TSHR | |
| SCHEMBL24999126 | 0.86 | EPHX1 (0.68) | EPHX1ACE2LMNAALDH1A1TSHR | |
| SCHEMBL21084325 | 0.86 | EPHX1 (0.68) | EPHX1ACE2LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031904-A1 | Mammalian IAP gene family, primers, probes and detection methods | OTTAWA, UNIVERSITY OF (CA) | 2007-02-08 | — | — | US | disclosed |