Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14616200 | 1.00 | EPHX1 (0.52) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL19198224 | 0.93 | EPHX1 (0.56) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL27334711 | 0.93 | EPHX1 (0.56) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL18758414 | 0.93 | EPHX1 (0.56) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL19427053 | 0.91 | EPHX1 (0.61) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL17808443 | 0.90 | EPHX1 (0.46) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL7026506 | 0.90 | EPHX1 (0.46) | EPHX1KISS1RHTR2AHRH1ACE2 | |
| SCHEMBL21985348 | 0.88 | EPHX1 (0.64) | EPHX1ACE2LMNAALDH1A1TSHR | |
| SCHEMBL24999126 | 0.86 | EPHX1 (0.68) | EPHX1ACE2LMNAALDH1A1TSHR | |
| SCHEMBL21084325 | 0.86 | EPHX1 (0.68) | EPHX1ACE2LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024055000-A1 | COMPOSITIONS AND METHODS COMPRISING LIPID NANOPARTICLE VACCINES THAT ELICIT A MODULATED IMMUNE RESPONSE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20230059865-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
| EP-3774843-B1 | DIPEPTIDE PIPERIDINE DERIVATIVES | MOLECURE SA (PL) | 2022-05-25 | — | — | EP | disclosed |
| US-11319303-B2 | Compound used as autophagy regulator, and preparation method therefor and uses thereof | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2022-05-03 | — | — | US | disclosed |
| US-20200190066-A1 | COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2020-06-18 | — | — | US | disclosed |
| EP-2675819-B1 | COMPOSITIONS AND METHODS FOR MOLECULAR LABELING | BIO RAD LABORATORIES (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-2961741-B1 | NOVEL COMPOUNDS AS DUAL INHIBITORS OF PHOSPHODIESTERASES AND HISTONE DEACETYLASES | FUND PARA LA INVESTIG MEDICA APLICADA (ES) | 2017-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319303-B2 | Compound used as autophagy regulator, and preparation method therefor and uses thereof | ATG7, SQSTM1, BECN1 | EPHX1 4533/4885KISS1R 3978/4885HTR2A 3454/4885 |
| US-20200190066-A1 | COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF | ATG7, SQSTM1, BECN1 | EPHX1 4533/4885KISS1R 3978/4885HTR2A 3454/4885 |
| US-20230059865-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SNRPA1 | EPHX1 2646/4885KISS1R 4547/4885HTR2A 3545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.