Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 8/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047180 | 1.00 | PTGFR (0.60) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL1047179 | 1.00 | PTGFR (0.60) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL1047178 | 1.00 | PTGFR (0.60) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL1043898 | 0.90 | PTGFR (0.58) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL1043901 | 0.90 | PTGFR (0.58) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL1043903 | 0.90 | PTGFR (0.58) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL1461634 | 0.90 | PTGFR (0.58) | PTGFRABCC4ABCB11PTGER3TBXA2R | |
| SCHEMBL1044518 | 0.88 | PTGFR (0.48) | PTGFRABCC4ABCB11PTGER3KDM4E | |
| SCHEMBL1460919 | 0.88 | PTGFR (0.48) | PTGFRABCC4ABCB11PTGER3KDM4E | |
| SCHEMBL1044517 | 0.88 | PTGFR (0.48) | PTGFRABCC4ABCB11PTGER3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032159-A1 | METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT | META COMESTICS, LLC (US) | 2011-03-17 | — | — | WO | disclosed |