SCHEMBL14616454

SCHEMBL14616454

COc1cc(C)c(C(c2cc(C3CCCCC3)c(OC)cc2C)c2ccccc2OC)cc1C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.43
HTR2C P28335 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PTGDR2 Q9Y5Y4 3/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
HIF1A Q16665 1/20 0.36
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
DRD2 P14416 1/20 0.35
ABCB1 P08183 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2620542 0.90 HTR2A (0.39) HTR2AHTR2CMEN1KMT2APTGDR2
SCHEMBL3273104 0.80 PTGDR2 (0.59) MEN1KMT2APTGDR2
SCHEMBL13655462 0.77 PTGDR2 (0.34) PTGDR2CHRM1LMNAADRA2A
SCHEMBL8006787 0.76 PTGDR2 (0.46) MEN1KMT2APTGDR2CHRM1HPGD
SCHEMBL18199345 0.74 PTGDR2 (0.42) HTR2AMEN1KMT2APTGDR2CHRM2
SCHEMBL757158 0.74 NUDT1 (0.37) MEN1KMT2APTGDR2LMNA
SCHEMBL30127784 0.74 NUDT1 (0.37) MEN1KMT2APTGDR2LMNA
SCHEMBL29375612 0.74 NUDT1 (0.37) MEN1KMT2APTGDR2LMNA
SCHEMBL14487083 0.74 PTGDR2 (0.43) MEN1KMT2APTGDR2
SCHEMBL19009196 0.74 HTR2A (0.34) HTR2AMEN1KMT2APTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170174807-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2017-06-22 US disclosed
US-20170088672-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2017-03-30 US disclosed
US-9527943-B2 Polymer, photosensitive resin composition and electronic device SUMITOMO BAKELITE CO., LTD. (JP) 2016-12-27 US disclosed
US-9366956-B2 Self-imageable layer forming polymer and compositions thereof PROMERUS, LLC (US) 2016-06-14 US disclosed
US-20150252132-A1 POLYMER, PHOTOSENSITIVE RESIN COMPOSITION AND ELECTRONIC DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2015-09-10 US disclosed
US-20140205948-A1 SELF-IMAGEABLE LAYER FORMING POLYMER AND COMPOSITIONS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2014-07-24 US disclosed
US-8715900-B2 Self-imageable layer forming polymer and compositions thereof PROMERUS, LLC (US) 2014-05-06 US disclosed
US-20130017488-A1 Self-Imageable Layer Forming Polymer and Compositions Thereof PROMERUS LLC (US) 2013-01-17 US disclosed