Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.68 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.68 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.68 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.56 |
| ▸ | TLR2 | O60603 | 5/20 | 0.56 |
| ▸ | RRM1 | P23921 | 1/20 | 0.55 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14205322 | 0.93 | GNAI3 (0.65) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL30094858 | 0.93 | GNAI3 (0.65) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL20980376 | 0.93 | GNAI3 (0.63) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL20980426 | 0.93 | GNAI3 (0.63) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL24379775 | 0.93 | GNAI3 (0.63) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL14616413 | 0.93 | GNAI3 (0.59) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL14616487 | 0.92 | GNAI3 (0.63) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL14240492 | 0.91 | GNAI3 (0.61) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL20980377 | 0.88 | GNAI3 (0.56) | GNAI3GNAO1GNAI1DPP7TLR2 | |
| SCHEMBL14616462 | 0.87 | GNAI3 (0.59) | GNAI3GNAO1GNAI1DPP7TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9393315-B2 | Compounds for targeting drug delivery and enhancing siRNA activity | NITTO DENKO CORPORATION (JP) | 2016-07-19 | — | — | US | disclosed |
| US-9393315-B2 | Compounds for targeting drug delivery and enhancing siRNA activity | NITTO DENKO CORPORATION (JP) | 2016-07-19 | — | — | US | disclosed |
| US-20130017249-A1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2013-01-17 | — | — | US | disclosed |
| US-20130017249-A1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130017249-A1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | LDLR, RARG, FABP4 | GNAI3 3017/4885GNAO1 3483/4885GNAI1 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.