Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30393814 | 0.82 | GRK5 (0.46) | MMP13PDK2PDK4MMP2MMP9 | |
| SCHEMBL25248135 | 0.79 | AR (0.49) | ARMMP13MMP2GSK3AGSK3B | |
| SCHEMBL11838692 | 0.79 | AR (0.53) | ARMMP13MMP2MMP9ALDH1A1 | |
| SCHEMBL25248589 | 0.79 | AR (0.57) | ARMMP13ALDH1A1GSK3AGSK3B | |
| SCHEMBL25249887 | 0.77 | ALDH1A1 (0.51) | ARALDH1A1GSK3AGSK3BGAA | |
| SCHEMBL25258942 | 0.77 | AR (0.55) | ARMMP2ALDH1A1GAA | |
| SCHEMBL30381901 | 0.77 | AR (0.55) | ARMMP2ALDH1A1GAA | |
| SCHEMBL30382173 | 0.77 | ALDH1A1 (0.51) | ARALDH1A1GSK3AGSK3BGAA | |
| SCHEMBL11465842 | 0.75 | AR (0.68) | ARCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL10338930 | 0.75 | MGLL (0.53) | ARPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570646-B2 | Compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2026-03-10 | — | — | US | disclosed |
| CN-116033899-B | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2024-11-05 | — | — | CN | disclosed |
| US-20230295142-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-09-21 | — | — | US | disclosed |
| US-20230295142-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-09-21 | — | — | US | disclosed |
| US-20230295142-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-09-21 | — | — | US | disclosed |
| EP-4208461-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2023-07-12 | — | — | EP | disclosed |
| CN-116033899-A | Novel compounds as inhibitors of histone deacetylase 6 and pharmaceutical compositions comprising the same | 株式会社 钟根堂 | 2023-04-28 | — | — | CN | disclosed |
| EP-3103797-B1 | 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3103797-A1 | 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2016-12-14 | — | — | EP | disclosed |
| EP-2776403-B1 | 2,5-DIOXOIMIDAZOLIDIN-1-YL-3-PHENYLUREA DERIVATIVES AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2016-09-14 | — | — | EP | disclosed |
| EP-1144366-A3 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2003-06-04 | — | — | EP | disclosed |
| WO-2003043983-A1 | PIPERAZINE DERIVATIVES DESTABILISING ANDROGEN RECEPTORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |
| WO-2001058855-A9 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA INC (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6472415-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2002-10-29 | — | — | US | disclosed |
| EP-1169301-A1 | A TOPICAL ANTIANDROGEN FOR HAIR LOSS AND OTHER HYPERANDROGENIC CONDITIONS | BIOPHYSICA, INC. (US) | 2002-01-09 | — | — | EP | disclosed |
| EP-1144366-A2 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2001058855-A1 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC (US) | 2001-08-16 | — | — | WO | disclosed |
| WO-2001058854-A1 | A TOPICAL ANTIANDROGEN FOR HAIR LOSS AND OTHER HYPERANDROGENIC CONDITIONS | BIOPHYSICA, INC. (US) | 2001-08-16 | — | — | WO | disclosed |
| US-6184249-B1 | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes | BIOPHYSICA, INC. | 2001-02-06 | — | — | US | disclosed |
| WO-2000037430-A2 | USE OF ANDROGEN RECEPTOR SUPPRESSORS | BIOPHYSICA, INC. (US) | 2000-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295142-A1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HDAC6, HDAC1, HDAC2 | AR 788/4885MMP13 1064/4885PDK2 646/4885 |
| US-12570646-B2 | Compounds as histone deacetylase 6 inhibitor, and pharmaceutical composition comprising the same | HDAC6, HDAC3, HDAC1 | AR 316/4885MMP13 662/4885PDK2 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.