Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N',N'-Dimethylbenzohydrazide SCHEMBL952727 | 0.78 | POLB (0.56) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| N',N'-Dimethylbenzohydrazide SCHEMBL27406776 | 0.76 | POLB (0.55) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| SCHEMBL11369151 | 0.73 | TDP1 (0.59) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| SCHEMBL10449073 | 0.73 | POLB (0.61) | KDM4EPOLBL3MBTL1TDP1HDAC3 | |
| SCHEMBL25150602 | 0.72 | KMT2A (0.50) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| SCHEMBL11585058 | 0.71 | POLB (0.53) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| SCHEMBL18327716 | 0.70 | KMT2A (0.55) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| SCHEMBL9516913 | 0.69 | L3MBTL1 (0.58) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| SCHEMBL12154023 | 0.69 | HSP90AA1 (0.70) | KDM4EPOLBL3MBTL1TDP1RAB9A | |
| SCHEMBL28202751 | 0.69 | NPC1 (0.53) | KDM4ERAB9AALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032413-A1 | Human secreted proteins | HUMAN GENOME SCIENCES, INC. | 2007-02-08 | — | — | US | disclosed |