Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4918743 | 0.80 | CYP3A4 (0.46) | KMT2APOLBTSHRL3MBTL1TDP1 | |
| N',N'-Dimethylbenzohydrazide SCHEMBL952727 | 0.79 | POLB (0.56) | KMT2APOLBL3MBTL1TDP1HDAC3 | |
| N',N'-Dimethylbenzohydrazide SCHEMBL27406776 | 0.78 | POLB (0.55) | KMT2APOLBL3MBTL1TDP1HDAC3 | |
| SCHEMBL11369151 | 0.74 | TDP1 (0.59) | KMT2APOLBL3MBTL1TDP1HDAC3 | |
| SCHEMBL10449073 | 0.74 | POLB (0.61) | POLBL3MBTL1TDP1HDAC3CA12 | |
| SCHEMBL11585058 | 0.72 | POLB (0.53) | KMT2APOLBL3MBTL1TDP1HDAC3 | |
| SCHEMBL14617232 | 0.72 | KDM4E (0.49) | KMT2APOLBL3MBTL1TDP1HDAC3 | |
| SCHEMBL810200 | 0.71 | ALDH1A1 (0.61) | KMT2APOLBTSHRHDAC3CA12 | |
| SCHEMBL6885505 | 0.71 | TSHR (0.58) | KMT2APOLBTSHRTDP1HDAC3 | |
| SCHEMBL9516913 | 0.71 | L3MBTL1 (0.58) | POLBL3MBTL1TDP1HDAC3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064164-A1 | CHIMERIC COMPOUNDS USEFUL IN TREATING DISEASES | PADARN THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |