Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178577 | 0.85 | ADRB2 (0.50) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL142928 | 0.85 | ADRB2 (0.50) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL1462012 | 0.84 | ADRB2 (0.44) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL146707 | 0.83 | ADRB2 (0.46) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL145085 | 0.83 | ADRB2 (0.46) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL13625783 | 0.83 | ADRB2 (0.46) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL141426 | 0.82 | ADRB2 (0.45) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL116323 | 0.82 | ADRB2 (0.45) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL149073 | 0.82 | ADRB2 (0.45) | ADRB2KCNH2KDM4EALDH1A1HPGD | |
| SCHEMBL178603 | 0.81 | ADRB2 (0.49) | ADRB2KCNH2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011031740-A1 | ANTIBACTERIAL FLUOROQUINOLONE ANALOGS | ACHAOGEN, INC. (US) | 2011-03-17 | — | — | WO | disclosed |