Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461599 | 0.82 | HSP90AB1 (0.39) | HSP90AB1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL12275366 | 0.78 | GAA (0.42) | HSP90AB1L3MBTL1GAACYP1A2ALDH1A1 | |
| SCHEMBL12275365 | 0.78 | HSP90AB1 (0.45) | HSP90AB1L3MBTL1GAACYP1A2ALDH1A1 | |
| SCHEMBL12451342 | 0.77 | CA1 (0.46) | HSP90AB1GAAALDH1A1RECQL | |
| SCHEMBL18839649 | 0.77 | HSP90AB1 (0.49) | HSP90AB1MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL16714956 | 0.76 | MEN1 (0.50) | MEN1NPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL1461801 | 0.73 | GAA (0.38) | HSP90AB1MEN1KMT2AGAACYP1A2 | |
| SCHEMBL20518699 | 0.72 | GAA (0.40) | HSP90AB1MEN1RAB9AKMT2AGAA | |
| SCHEMBL25214310 | 0.71 | HSP90AB1 (0.37) | HSP90AB1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1461856 | 0.71 | GAA (0.40) | HSP90AB1MEN1KMT2AGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029639-A2 | COMPOUNDS AND METHODS FOR TREATING NEOPLASIA | MEDEXIS S.A. (GR) | 2011-03-17 | — | — | WO | disclosed |