Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461597 | 0.83 | PDE4A (0.35) | ALDH1A1CYP1A2CYP2C9HSP90AB1KMT2A | |
| SCHEMBL1461856 | 0.81 | GAA (0.40) | GAAALDH1A1CYP1A2CYP2C9RECQL | |
| SCHEMBL12275365 | 0.75 | HSP90AB1 (0.45) | GAAALDH1A1CYP1A2CYP2C9RECQL | |
| SCHEMBL1461804 | 0.73 | HSP90AB1 (0.47) | GAAALDH1A1CYP1A2CYP2C9RECQL | |
| SCHEMBL12275366 | 0.73 | GAA (0.42) | GAAALDH1A1CYP1A2CYP2C9RECQL | |
| SCHEMBL4267815 | 0.73 | GAA (0.47) | GAAALDH1A1CYP1A2CYP2C9RECQL | |
| SCHEMBL12451342 | 0.73 | CA1 (0.46) | GAAALDH1A1RECQLHSP90AB1POLB | |
| SCHEMBL18839649 | 0.72 | HSP90AB1 (0.49) | GAAALDH1A1RECQLHSP90AB1KMT2A | |
| SCHEMBL20518699 | 0.69 | GAA (0.40) | GAAALDH1A1CYP1A2CYP2C9RECQL | |
| SCHEMBL26347332 | 0.67 | DGAT1 (0.51) | ALDH1A1HSP90AB1MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011029639-A2 | COMPOUNDS AND METHODS FOR TREATING NEOPLASIA | MEDEXIS S.A. (GR) | 2011-03-17 | — | — | WO | disclosed |