Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 17/20 | 0.55 |
| ▸ | CDK9 | P50750 | 7/20 | 0.46 |
| ▸ | CCNK | O75909 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461838 | 0.89 | CCNT1 (0.68) | CCNT1CDK9CCNK | |
| SCHEMBL1463040 | 0.88 | CCNT1 (0.55) | CCNT1CDK9CCNK | |
| SCHEMBL1463704 | 0.80 | CCNT1 (0.57) | CCNT1CDK9CCNK | |
| SCHEMBL1461943 | 0.80 | CCNT1 (0.57) | CCNT1CDK9CCNK | |
| SCHEMBL12850511 | 0.80 | CCNT1 (0.59) | CCNT1CDK9 | |
| SCHEMBL1462808 | 0.78 | CCNT1 (0.59) | CCNT1CDK9 | |
| SCHEMBL10180910 | 0.78 | CCNT1 (0.59) | CCNT1CDK9 | |
| SCHEMBL1947509 | 0.77 | CCNT1 (0.44) | CCNT1CDK9 | |
| SCHEMBL1947637 | 0.77 | CCNT1 (0.44) | CCNT1CDK9 | |
| SCHEMBL1461835 | 0.77 | CCNT1 (0.44) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |