Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.35 |
| ▸ | ATP4B | P51164 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148677 | 0.93 | KMT2A (0.33) | ATP4AATP4BKMT2AMEN1PKM | |
| SCHEMBL1148508 | 0.82 | KMT2A (0.33) | ATP4AATP4BKMT2AMEN1PKM | |
| SCHEMBL12287233 | 0.82 | ATP4A (0.33) | ATP4AATP4B | |
| SCHEMBL421149 | 0.80 | MEN1 (0.32) | ATP4AATP4BKMT2AMEN1GAA | |
| SCHEMBL445552 | 0.79 | MEN1 (0.32) | ATP4AATP4BKMT2AMEN1GAA | |
| SCHEMBL14525272 | 0.79 | CCNB2 (0.35) | ATP4AATP4BKMT2AMEN1GAA | |
| SCHEMBL445551 | 0.79 | MEN1 (0.32) | ATP4AATP4BKMT2AMEN1GAA | |
| SCHEMBL13639211 | 0.77 | MAPT (0.33) | ATP4AATP4BKMT2AMEN1 | |
| SCHEMBL1148670 | 0.77 | HSP90AA1 (0.44) | ATP4AATP4B | |
| SCHEMBL12287725 | 0.75 | KDM4E (0.43) | KMT2AMEN1NCOA1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007021877-A1 | IMIDAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY | SYNTA PHARMACEUTICALS CORP. (US) | 2007-02-22 | — | — | WO | disclosed |