Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14618753 | 0.87 | MEN1 (0.37) | MEN1KMT2ASLC18A3ESR2MAPT | |
| SCHEMBL14618504 | 0.84 | SPHK1 (0.41) | DRD2SPHK1CYP2C9 | |
| SCHEMBL14618505 | 0.83 | SPHK1 (0.43) | SPHK1 | |
| SCHEMBL10017471 | 0.83 | SPHK1 (0.41) | ESR2SPHK1 | |
| SCHEMBL18361625 | 0.82 | DRD2 (0.49) | SLC18A3DRD2 | |
| SCHEMBL10017493 | 0.81 | DRD2 (0.55) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL17430686 | 0.81 | NQO1 (0.50) | MAPTDRD2KCNH2CYP2C9CYP3A4 | |
| SCHEMBL1405569 | 0.81 | ESR2 (0.50) | SLC18A3ESR2MAPTALDH1A1LMNA | |
| SCHEMBL13402045 | 0.81 | SPHK1 (0.44) | SPHK1 | |
| SCHEMBL4549740 | 0.80 | SLC18A3 (0.41) | MEN1KMT2ASLC18A3ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754768-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY | Dainippon Ink and Chemicals, Incorporated (JP) | 2007-02-21 | — | — | EP | disclosed |