Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11960641 | 0.92 | MARS1 (0.33) | CNR2MC4RMC5RMC3R | |
| SCHEMBL20124187 | 0.91 | MC4R (0.32) | MC4RMC5RMC3R | |
| SCHEMBL11960637 | 0.86 | PDCD1 (0.37) | MC4RMC5RMC3RKDM4ENPC1 | |
| SCHEMBL19573483 | 0.85 | MC4R (0.34) | MC4RMC5RMC3R | |
| SCHEMBL14613 | 0.85 | MC4R (0.34) | MC4RMC5RMC3R | |
| SCHEMBL11960639 | 0.84 | CHRM2 (0.38) | MC4RMC5RMC3RKDM4EALDH1A1 | |
| SCHEMBL20124107 | 0.84 | HDAC1 (0.34) | CNR1MC4RMC5RMC3RVSIR | |
| SCHEMBL11960642 | 0.83 | HDAC1 (0.34) | MC4RMC5RMC3R | |
| SCHEMBL11208 | 0.82 | MC4R (0.33) | MC4RMC5RMC3R | |
| SCHEMBL11960640 | 0.82 | MAP3K11 (0.35) | KDM4EPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488532-B1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2018-05-09 | — | — | EP | disclosed |
| WO-2011047320-A2 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2011-04-21 | — | — | WO | disclosed |