Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1192283 | 0.85 | KCNH3 (0.48) | CCNT1KCNH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1191759 | 0.83 | KCNH3 (0.37) | CCNT1KCNH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1461912 | 0.78 | CCNT1 (0.44) | CCNT1KDM1AMAOAMAOBJAK1 | |
| SCHEMBL29265648 | 0.74 | CYP1A2 (0.52) | CHRM1PIM1 | |
| SCHEMBL7010205 | 0.73 | SLC6A2 (0.44) | CCNT1SLC6A2SLC6A4SLC6A3PIM1 | |
| SCHEMBL3114904 | 0.72 | POLB (0.54) | PIM1 | |
| SCHEMBL19426727 | 0.71 | APP (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25298737 | 0.71 | MEN1 (0.46) | CCNT1SLC6A2SLC6A4SLC6A3PIM1 | |
| SCHEMBL5352788 | 0.70 | KDM4C (0.44) | — | |
| SCHEMBL1463733 | 0.70 | ALDH1A1 (0.51) | CCNT1SLC6A2SLC6A4SLC6A3CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |