Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14619400 | 0.90 | PTGS1 (0.46) | ALDH1A1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL14619340 | 0.88 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTCYP3A4 | |
| SCHEMBL14619341 | 0.87 | PTGS1 (0.44) | ALDH1A1SMN1; SMN2PTGS1PTGS2TUBB4A | |
| SCHEMBL14619348 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL412021 | 0.86 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2FLT3PTGS1PTGS2 | |
| SCHEMBL14619347 | 0.84 | KCNMA1 (0.53) | ALDH1A1PTGS2TUBB4ATUBBTUBA3C | |
| SCHEMBL14619344 | 0.84 | CYP3A4 (0.41) | ALDH1A1SMN1; SMN2TUBB4ATUBBTUBA3C | |
| SCHEMBL14619397 | 0.83 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PTGS1PTGS2MAPT | |
| SCHEMBL13040943 | 0.81 | FLT3 (0.54) | ALDH1A1SMN1; SMN2FLT3PTGS1PTGS2 | |
| SCHEMBL14619077 | 0.80 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2FLT3PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007014198-A1 | 1, 2, 3 -TRIAZOLES INHIBITORS OF TUBULIN POLYMERIZATION FOR THE TREATMENT OF POLIFERATIVE DISORDERS | SYNTA PHARMACEUTICALS CORP. (US) | 2007-02-01 | — | — | WO | disclosed |