Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6807118 | 0.92 | CA1 (0.41) | CA1CA2APLNRTBXAS1IDO1 | |
| SCHEMBL7190403 | 0.92 | CA1 (0.41) | CA1CA2APLNRTBXAS1IDO1 | |
| SCHEMBL6807121 | 0.92 | CA1 (0.41) | CA1CA2APLNRTBXAS1IDO1 | |
| SCHEMBL7190400 | 0.92 | CA1 (0.41) | CA1CA2APLNRTBXAS1IDO1 | |
| SCHEMBL7190398 | 0.92 | CA1 (0.41) | CA1CA2APLNRTBXAS1IDO1 | |
| SCHEMBL7198518 | 0.88 | CA1 (0.40) | CA1CA2APLNRFFAR1TBXAS1 | |
| SCHEMBL7198525 | 0.88 | CA1 (0.40) | CA1CA2APLNRFFAR1TBXAS1 | |
| SCHEMBL7096896 | 0.88 | CA1 (0.40) | CA1CA2APLNRTBXAS1IDO1 | |
| SCHEMBL5997017 | 0.88 | CA1 (0.40) | CA1CA2APLNRTBXAS1IDO1 | |
| SCHEMBL6810807 | 0.86 | CA1 (0.38) | CA1CA2APLNRTBXAS1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070043223-A1 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043223-A1 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof | LSS, DHPS, ERG28 | CA1 2057/4885CA2 4276/4885APLNR 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.